药物的变质反应和生物转化.pptVIP

Medicinal chemistry is a chemistry-based discipline, also involving aspects of biological, medical and pharmaceutical sciences. It is concerned with the invention, discovery, design, identification and preparation of biologically active compounds, the study of their metabolism, the interpretation of their mode of action at the molecular level and the construction of structure-activity relationships. 国外制药巨头 Merck JohnsonJohnson Pfizer Bristol Myers Squibb Pharmacia Abbott Laboratories Wyeth Eli Lilly Schering-Plough Novartis Bayer Roche GlaxoSmithKline 新药研发 意外事件：沙利度胺----海豹胎 变质反应直接