ppt课件-kuruandcjdprionviruses-strongsvillecityschools.pptVIP

CJD and Kuru: Prion Viruses By: Danny Nemeth Prion infectious agent composed of protein in a misfolded form CJD Creutzfeldt-Jakob Disease neurodegenerative disorder year of onset of illness Structure no Nucleic acids mass of 27,000 - 30,000 daltons 145 amino acids Structure unknown Cause promotes refolding of native proteins mass of misfolded proteins disrupts cell function ALWAYS FATAL! Symptoms Neurological Depression Confusion loss of coordination and balance progressive blindness Transmission GENETICS! Defective HGH CANNIBALISM! KURU Misfolded Proteins Cannibalism Brains