肿瘤病因学-陈丽荣.pptVIP

Cancer Risk Factors (NIH) Growing older Tobacco Sunlight Ionizing radiation Certain chemicals and other substances Some viruses and bacteria Certain hormones Family history of cancer Alcohol Poor diet, lack of physical activity, or being overweight 化学因素 天然化合物: 天然的黄曲霉毒素 含麻兜铃碱的草药 二氧化硅 结晶型（职业接触吸入的石英或方晶石尘） 含石棉状纤维的滑石 Hereditary Diffuse Gastric CA. It is an autosomal-dominant cancer susceptibility syndrome that is characterized by signet ring cell gastric cancer and lobular breast cancer. Accounts for 1-3% Germline mutation of E-cad(CDH1) gene discovered by Gu