米氮平与文拉法辛治疗抑郁症对比研究.pdfVIP

JClin Dis，Mar．2006，Vt，fI2．M．2 11l 临床心身疾病杂志2006牛3，j第12卷第2期Psychosom 米氮平与文拉法辛治疗抑郁症对照研究 吴字博 【摘要1目的探讨米氨平与文拉法辛治疗抑郁症的疗效与不良反应。方法将100例抑郁症患者随机分为米氮平组和文拉 {击辛组。于治疗l，2，6w末采用汉密尔顿抑郁量表和剐反应量表评定临床疗效与不良反应。结果治疗2w末时．文拉法辛 应均较轻微，且差异无显著性(P0．05)。结论米氮平与文拉法辛的抗抑部疗效肯定，不良反应轻微。 ‘关键调】米氨平I文拉法辛，抑郁症 【中用分类号】R749．4 【文献标识码】A【文章编号】1672—187X(2006)02—0111—02 Controlledof in VS．venlafaxinethetreatmentof mirtazapine study WuYi幻 3rd (ThePeople’sHospitalofHeze．Shandong，China) To effieaciesandsideeffectsof vs．venlafaxineinthe [Abstract]Objectiveexplore mirtazapine of 100 with depression．Methods were dividedinto andven— patientsdepressionrandomly mirtazapine lafaxine andsideeffectswereassessedwiththeHamilton group．Effieacies Depression Treatment theendsofthe and6th EmergentSymptomScale(TESS)at 1st．2nd weekof suitsAttheendofthe 2nd ratedecreasedmore inthevenlafaxinethan week，score—reducing significantly inthe differencewas mirtazapine theendofthe6th was group，and significant(P0．05)；atweek．there no differenceinscore ratebetween2 significant reducing thegroups(P0．05)．After andeffectiveratesofthe were thoseof mirtazapinegroup 64％and88％and thevenlafaxine60V0and80％ showedno effectsof 2 respectively，which difference．Sideboth weremilderandhadno significant groups Both andvenlafaxinehave significantdifference(P0．05)．Conclusion bett