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目 录
中文 摘 要 ········································································… … IV
英 文摘 要 ·········································································… …V
第 一 章 绪 论 ······································································… …
1.1 阿霉 素 药物 简介 .. ····························································… … 1
1.1.1 阿霉 素 的结构性质 及合 成 ···············································… …
1.1.2 阿霉 素 的毒 副作用及其 防止 ···········································… … 2
1.2 新 型 的阿霉 素药物模 型 ····················································… … 3
1.2.1 磁 性 毫 微粒 和磁 性毫微球 ·············································… … 4
1.2.2 脂 质 体 ·····································… … !’’·····················… … 4
1.2.3 凝 胶 缓释 ·································································… … 5
1.3 可 注 射 性 水 凝 胶 ·····························································… … 5
1.3.1天 然 及 半 天 然 和 合 成 的可注 射 性 水 凝 胶 ······························… … 6
多糖类 ·······························································… … 6
.1 海 藻酸盐类 ·····················································… … 6
.2 透 明质 酸 .. ·····················································… … 7
.3 壳 聚糖 ··························································… … 7
.4 纤 维 素 ·····················································… … 7
P E G /PP G 嵌 段 共 聚物 ··············································… … 8
PE G /聚酷 可 降解 嵌段共 聚物 ·······································… …
聚 多肤/氨基 酸 为基础 的可 降解 嵌段共 聚物 ······················… … 9
聚 有机 磷 睛 ·························································… … 9
1.4 研 究 目的 ·····································································… … O
参 考 文 献 ········································································… … 12
第 二 章 P L G A 一P E G 一P L G A 三 嵌段 共 聚物 的合 成 与表 征 ····················… …
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