elevated radial arterial augmentation index in hypertensive patients with diastolic dysfunction期刊.pdfVIP

J our na l of Ger i at r i c Car di ol o gy J une 2008 Vol 5 No 2 67 Ct i ni c al Res ear ch El evat e d r adi a l ar t er i al augment at i on i nde i n hyper t ens i ve pat i ent s wi t h di a st ol i c dys f unc t i on Qi ang Zeng ，Xi aonan Sun ，Li Fan ，Xi nmi ng Wan g，Pi ng Ye The Sec ond De par t men t of Ger i at r i cs Car di ol ogy , Chi ne se 肌 Gener al Hospi t al , BeUi ng 100853 ．Chi na obj ec t i ve To i nvest i gat e t he cor r el at i on bet ween au gment at i on i nde ( AI )of t he r adial ar t er y and di ast ol i c hear t f u nct i o n i n pat i ent s wi t h hyper t ens i on ． Met hods Echoc ar di ogr a phs we r e ob t a i ne d f or 305 pat i ent s wi t h hype r t ensi on ．AI ，pul se wave vel oc i t y ( PWV) of per i pher al ar t eri e s and s er umpr o—br ai n natn ’ur et i c pept i de ( pr oBNP) l eve l s wer e de t er mi n ed．Cor r e l at i on s and r e cei ve r op er at i ng char act er i s t i c ( ROC) cur ves wer e dr awn bet ween AI va l ue s and i mpa i r ed di ast ol i c f unct i on． Res ul t s AI l evel s wer e si gni f i cant l y i nc r eas ed i n pat i ent s wi t h i mp ai r e d di ast ol i c f un ct i on di a gnose d by ul t r as ou nd ．Ass es sment of di ast ol i c he ar t f u nct i o n bas e d on pr oBNP l evel s r ev eal ed t hat AI and a ort i c pu l se wave vel o ci t y we r e s i gni f i cant ly el evat e d i n pat i ent s wi t h i mpai r e d di ast ol i c fu nct i on．The op er at i ng