老年人维生素Ｄ缺乏的治疗策略.pptVIP

老年人维生素Ｄ缺乏的治疗策略;内 容;内 容;维生素D的代谢、调控及状态的评价;;;维生素D的代谢、调控及状态的评价;内 容;老年人维生素D代谢特点;老年人维生素D缺乏的病理机制; ;PTH(1-34)注射后老年人和年轻人血1,25(OH)D浓度变化;Ebeling P, Sandgren M, Dimagno E, et al . Evidence of an age-related decrease in intestinal responsiveness to vitamin D. J Clin Endocrinol Metab,75:176-182 .;1,25(OH)2D3干预后不同年龄人群成骨细胞骨钙素表达的比较;HA Bischoff-Ferrari, M Borchers, F Gudat, et al. Vitamin D Receptor Expression in Human Muscle Tissue Decreases With Age. JOURNAL OF BONE AND MINERAL RESEARCH. 2004,19(2):265-269.;老年人跌倒发生率随年龄增长而增加;跌倒与骨折;Laurent, Erich, Hannes. In elderly men and women treated for osteoporos