应用DUR与DUE方法评价我院慢性阻塞性肺疾病患者用药情况.pdfVIP

中国药物应用与监测 2013 年6 月第10卷第3 期 Chinese Journal of Drug Application and Monitoring, Vol.10, No.3, June 2013 ·临床评价 · 应用DUR 与DUE 方法评价我院慢性阻塞性肺疾病患者用药情况 1 1 2 （1.南京大学医学院附属鼓楼医院药学部，江苏 南京 210008 ；2. 中国药科大学药学院，江苏 南京 210008 ） 张晋萍 ，张海霞 ，蒙 龙 [摘要]　目的：评价我院100例慢性阻塞性肺疾病（COPD ）患者的用药合理性。方法：采用药物利用评价（DUR ）和药物利用 评估（DUE ）方法，评价我院2012 年1 月1 日– 3 月31 日出院的100例COPD 患者的用药情况。结果：100例患者所用35 种药 物中，32 种药物DUI ≤1，3 种药物DUI 1；所有患者都进行了血常规、肝肾功能的评估。在治疗过程中，血常规、肝功能、 肾功能、血钾水平及病原学的监测率分别为67.0%、37.0%、74.0%、77.0% 和93.3%。DDDs 居前三位的药物为孟鲁司特钠、多 索茶碱、盐酸氨溴索。采用DUE 方法评价，90 例（90% ）COPD 患者经治疗后临床症状得到改善，53 例（53% ）患者并发症治 愈。结论：联合应用DUR 和DUE 方法可以更全面地评价COPD 患者的用药情况。 [关键词]　慢性阻塞性肺疾病；药物利用评价；药物利用评估；药物利用指数 [ 中图分类号]　R974 [ 文献标识码]　A [ 文章编号]　1672 – 8157(2013)03 – 0128 – 04 Evaluation of the drug utilization in COPD patients by DUR and DUE 1 1 2 1. Pharmacy Department, Nanjing Drum Tower Hospital Affiliated to Medical ZHANG Jin-ping , ZHANG Hai-xia , MENG Long （ College of Nanjing University, Nanjing 210008, China; 2. Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing 210008, China ） [ABSTRACT]　Objective: To evaluate the rationality of the drug utilization in 100 patients with COPD in our hospital. Methods: The drug utilization of 100 patients with COPD in our hospital collected from January 1, 2012 to March 31, 2012 was evaluated by drug utilization review (DUR) and drug use evaluation (DUE). Results: Among the 35 kinds of drugs involved in 100 patients, values of DUI of 3 kinds of drugs were more than 1, while values of DUI of other 32 kinds of drugs were less than 1 or equal to 1, and all the patients underwent the blood routine detection and evaluation of liver and kidney function. During the therapeutic process, the monitoring percentages of blood routine detection, liver function, kidney function, potassium levels and pathogen