白浓度变化与梗死面积的相关性研究.pdfVIP

·386· 蝤鏖凼型盘查2塑生鱼旦筮堑鲞筮鱼翅』鱼丛堕丝些丛鲴：』坠堡2塑：!丛：堑：塑壁：鱼 ·论著· 急性心肌梗死患者C反应蛋白浓度变化 与梗死面积的相关性研究 韩丹娅童传凤王化敏 [文献标识码]A doi：10．3969／j．issn．1001-9057．2009．06．008 [中图分类号]R542．22 [摘要] 目的通过磁共振延迟强化成像(DE—MRI)技术定量评估急性心肌梗死(AMI)患者 存活心肌和梗死面积，探讨AMI患者C反应蛋白浓度的高低与心梗面积的相关性。方法采用免 疫荧光比浊法检测40例AMI患者血清CRP水平。将AMI患者分成高CRP组和低CRP组，并对所 有患者行DE-CMRI定量分析梗死面积，研究其与CRP浓度之间相关性。结果AMI高浓度CRP 患者与低浓度CRP相比在心脏梗死质量，梗死百分比，灌注缺损段及室壁运动评分比较差异有统 计学意义，高浓度CRP患者在梗死质量和面积上远较低浓度CRP者大。结论急性心肌梗死后梗 死面积和质量与CRP浓度成正比关系。 [关键词】急性心肌梗死；磁共振延迟强化成像；C反应蛋白 ofthe concentrationofAMI TheresearchcorrelationbetweenC·reactive andinfarctsize protein 础ⅣDanya，TONGChuanfeng，鼢们Huamin．DepartmentofRheumatology，the够2池dHospitalof Wuhantechlologyandscience．Wuhan430064．China To assessment necrosisofacute 『Abstract]Objective infac． quantitative myocardial myocardial tions contrast-enhancedresonance theeorrela- usingdelayed magnetic imaging(DE·MRI)，Toinvestigate tionbetweeninfarctsizeasassessedDE．MRI．andC．reactiveconcentration．MethodsThe by protein of weredividedinto CfuPlevel withAMI weredetected．Patients CRP fortypatients patients high subgroup thecorrelationbetween andlowCRP tohsCRPlevels．To two subgroupaccording investigate groupspa- size DE．MRI．ResultsCRP tientsC．reactive concentrationandinfarctasassessed sub． protein by High of ininfact was thanthatlowCRP size，infact groupsignificanthisher subgroup mass，perfusion—defec