纪立农从高血糖与糖尿病周围神经病变的关系反思研究和控制策略.pptVIP

* * Kaplan-Meier Estimates of the Composite End Point of Death from Cardiovascular Causes, Nonfatal Myocardial Infarction, Cor ry-Artery Bypass Grafting, Percutaneous Coronary Intervention, Nonfatal Stroke, Amputation, or Surgery for Peripheral Atherosclerotic Artery Disease in the Conventional-Therapy Group and the Intensive-Therapy Group * * Strong clinical evidence : The DCCT and the UKPDS established that hyperglycemia, shown on the far left of the figure, is the initiating cause of the diabetic tissue damage that we see clinically such as: damage to capillary endothelial cells in the retina, mesangial cells in the renal glomerulus, and neurons and Schwann cells in peripheral nerves. This process is modified by both genetic determinants of individual susceptibility, and by independent accelerating factors such as hypertension, shown in the bottom box, These are associated with repeated… that lead to Cumulative…. And among the 从高血糖与糖尿病周围神经病变的关系反思研究和控制策略 北京大学人民医院 纪立农 China Cardiometabolic Registries * Nation-wide, prospective, registry series designed to better understand clinical outcomes of current treatment of cardiovascular and metabolic diseases in real world settings Organized by Chinese Medical Doctor Associations Supervised by CCMR International Advisory Board Managed by VitalStrategic Research Institute China Cardiometabolic Registries 研究者会议2011 年 5 月 14-15 日 中国2型糖尿病患者心血管疾病危险因素的纵向队列研究 中国老年学学会（GSC）主办 中国医师协会心血管内科医师分会(CCCP) 协办 中国医师协会内分泌及代谢科医师分会(CEA) 协办 中国心血管代谢病系列研究(CCMR) 组织及专家委员会 指导 华斯泰生命策略研究所/上海华斯泰医学咨询有限公司 (VSRI) 执行 默沙东(中国)有限公司赞助 Nationwide Assessment of Cardiovascular Risk Factors--Blood Pressure, Blood Lipid, and Blood Glucose in Chinese Patients with Type 2 Diabetes Linong Ji Peking University People’s HospitalOn behalf of CCMR Advisory Board Ji et al. AJM，2013，in press Study Objectives – Primary Primary Objective To assess the level of control of CVD risk factors, including blood pressure, blood lipid, and blood glucose, in out