原创力文档a retrospective comparison of 2 methods of intraoperative margin evaluation during partial nephrectomy：部分切除术2种术中切缘评价方法的回顾性比较.pdfVIP
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a retrospective comparison of 2 methods of intraoperative margin evaluation during partial nephrectomy：部分切除术2种术中切缘评价方法的回顾性比较
A Retrospective Comparison of 2 Methods
of Intraoperative Margin Evaluation During Partial Nephrectomy
Ian S. Hagemann* and James S. Lewis, Jr.†
From the Division of Anatomic and Molecular Pathology, Department of Pathology and Immunology, Washington University School of
Medicine, St. Louis, Missouri
Abbreviations Purpose: Intraoperative pathological consultation is often used to achieve neg-
and Acronyms ative margins during partial nephrectomy. Commonly a tumor bed biopsy for
GIC gross intraoperative frozen section is taken from the most suspicious area of the defect. Alternatively
consultation the pathologist may perform prosection of the intact partial nephrectomy speci-
GIC-WWF GIC with or without men and prepare frozen sections of suspicious areas. We determined the sensi-
frozen section tivity and specificity of these 2 methods and a combined method.
Materials and Methods: Records of 251 cases performed at a single institution
RCC renal cell carcinoma
between 2005 and 2007 were retrospectively analyzed.
TBB tumor bed biopsy Results: Of the patients 56% were male. Mean age was 58.8 years. Laparoscopic
resection was performed in 76% of cases. Mean greatest tumor dimension was 2.9
Submitted for publication June 4, 2008. cm. Tumor bed biopsy was done in 120 cases, of which 15 (12.5%) showed positive
Study received institutional rev
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