CTA原始成像用于预测急性脑梗死患者的最终梗死体积.docVIP

CTA原始成像用于预测急性脑梗死患者的最终梗死体积 　　[摘要]目的探讨急性前循环闭塞性脑梗死患者血管CT的原始成像（Source images of CT Angiography，CTA_SI）下得到的梗死体积能否用于预测最终梗死体积。方法回顾性分析98例前循环急性闭塞的脑梗死患者。利用CTA_SI测量超早期的梗死体积。测量3～7天时DWI下的梗死体积。Person相关性检验分析两种影像参数结果的相关性。利用多元逻辑回归及多元线性分析，评估CTA_SI下的梗死体积与临床预后和最终梗死体积的相关性。结果98例患者中，女性46例（4694%），平均年龄（6502±1414）岁，基线期NIHSS评分为（1541±522）分。其中50例临床预后良好（mRS≤2），48例临床预后较差（mRS2）。CTA_SI与DWI测得的梗死体积有较好的相关性（P001，R2=070，95%可信区间：077 to 089）。CTA_SI下的梗死体积是临床预后及最终梗死体积最重要的预测因素（P001）。结论急性缺血性脑卒中超早期的CTA_SI可用于最终梗死体积及临床预后的预测，有利于制定合理的治疗决策。 　　[关键词]急性脑梗死；CT血管成像；梗死体积 　　中图分类号：R7433；R81442文献标识码：A文章编号：1009_816X（2016）02_0091_04 　　doi：103969/jissn1009_816rediction Effect of Original CT Angiography Image on Final Infarct Volume Assessment in Acute Cerebral Infarction Patients. SUN Yong， LI Hui_ming， WANG Li_qiang， et al Yanjiao People’s Hospital， Hebei 065201， China 　　[Abstract] Objective To investigate whether the infarct volumes conducted by CTA_SI of acute cerebral anterior circulation occlusion can predict the final infarct volume Methods A retrospective analysis of 98 patients with cerebral infarction caused by acute occlusion of anterior circulation was conducted in this study Their infarct volumes in earlier stage were determined by CTA_SI and final infarct volumes were evaluated on DWI in 3 to 7 days since onset The correlations between these two image parameters were tested by Pearson correlation analysis Multi_variables logistic regression analysis and multi_variables linear regression analysis were applied to determine whether infarct volume on CTA_SI can predict the clinical and imaging outcome Results Of the 98 cases， 46 were female（4694%） Mean age of all was （6502±1414） years old NIHSS value of the baseline period was （1541±522） Among all， the clinical outcome of 50 cases were good （mRS≤2） while 48 cases were poor （mRS2） Infarct volume on CTA_SI showed good correlation with that on DWI （P001， R2=070， 95% CI： 077 to 089） The infarct volume on CTA_SI was the most important predictive factor f