Ⅰ类切口手术抗菌药物合理预防性应用调查分析.docVIP

Ⅰ类切口手术抗菌药物合理预防性应用调查分析 　　[摘要] 目的 探讨在该院的手术条件下，预防性应用抗菌药物对Ⅰ类清洁切口手术患者切口感染的影响。 方法 随机抽取该院2013年1月―2015年12月间收治的653例Ⅰ类清洁切口手术，按照患者有无高危因素、是否预防性应用抗菌药物进行分组，统计各组患者切口感染率，进行对比分析。结果 有高危因素的Ⅰ类清洁切口手术未预防性应用抗菌药物组比有高危因素的Ⅰ类清洁切口手术预防性应用抗菌药物组患者切口感染率提高了17.28%；无高危因素的Ⅰ类清洁切口手术未预防性应用抗菌药物组比无高危因素的Ⅰ类清洁切口手术预防性应用抗菌药物组患者切口感染率只提高了0.31%。结论 在该院的手术条件下，有高危因素的Ⅰ类清洁切口手术应预防性应用抗菌药物，可有效地降低患者切口感染率；无高危因素的Ⅰ类清洁切口手术可无需应用抗菌药物进行手术预防，切口感染率变化不大，验证了Ⅰ类清洁切口手术预防用药指征在该院的适用性。 　　[关键词] Ⅰ类清洁切口手术；预防性应用抗菌药物；对比分析 　　[中图分类号] R978.1 [文献标识码] A [文章编号] 1674-0742（2016）04（c）-0038-03 　　[Abstract] Objective To study the effect of predictive application of antibacterials on the incision infection of patients with type I clean incision operation in the operative conditions of our hospital. Methods 653 cases of patients with type I clean incision operation treated in our hospital from January 1， 2013 to December 31， 2015 were randomly extracted and divided into groups according to whether the patients had the high-risk factors or not and whether they predictively applied antibacterials， and the incision infection rate of each group was counted， compared and analyzed. Results The incision infection rate of the group with type I clean incision operation with high-risk factor and without predictive application of antibacterials increased by 17.28% compared with that of the group with type I clean incision operation with high-risk factor and with predictive application of antibacterials， but the incision infection rate of the group with type I clean incision operation without high-risk factor and without predictive application of antibacterials only increased by 0.31% compared with that of the group with type I clean incision operation without high-risk factor and with predictive application of antibacterials. Conclusion In the operative conditions of our hospital， the type I clean incision operation with high-risk factor should predictively apply antibacterials， and it can effectively reduce the incision infection rate of patients， the type I