兰索拉唑联合莫沙比利治疗反流性食管炎的效果观察.docVIP

兰索拉唑联合莫沙比利治疗反流性食管炎的效果观察 　　【摘要】 目的：探讨兰索拉唑联合莫沙比利治疗反流性食管炎的临床效果。方法：选取笔者所在医院2013年2月-2015年2月收治的126例反流性食管炎患者作为研究对象，按照随机数字表法将其分为观察组和对照组，每组63例。对照组给予兰索拉唑治疗，观察组给予兰索拉唑和莫沙必利联合治疗，疗程均为14 d。评定两组患者的临床疗效及内镜下治疗效果。结果：观察组的治疗总有效率为95.2%，明显高于对照组的71.4%，差异有统计学意义（P0.05）。观察组内镜下总有效率为93.7%，明显高于对照组的68.3%，差异有统计学意义（P0.05）。结论：兰索拉唑联合莫沙必利能够显著改善反流性食管炎患者的临床症状，治疗效果显著，值得借鉴推广。 　　【关键词】 反流性食管炎； 兰索拉唑； 莫沙必利； 治疗效果 　　中图分类号 R571 文献标识码 B 文章编号 1674-6805（2016）12-0023-02 　　Curative Effect Observation of Lansoprazole Combined with Mosapride in the Treatment of Reflux Esophagitis/HU Jian.//Chinese and Foreign Medical Research，2016，14（12）：23-24 　　【Abstract】 Objective：To investigate the clinical effect of Lansoprazole combined with Mosapride in the treatment of reflux esophagitis.Method：From February 2013 to February 2015，126 patients with reflux esophagitis admitted to our hospital were selected as research objects，and they were divided into the observation group and the control group according to the random number table method，63 cases in each group.The control group was given Lansoprazole for treatment，the observation group was given Lansoprazole and Mosapride for treatment.The course of treatment was 14 days.The clinical efficacy and treatment effect under gastroscopy between the two groups were evaluated.Result：The total effective rate of the observation group was 95.2%，which was significantly higher than 71.4% of the control group，the difference was statistically significant（P0.05）.The total effective rate of the observation group under gastroscopy was 93.7%，which was significantly higher than 68.3% of the control group，the difference was statistically significant（P0.05）.Conclusion：Lansoprazole combined with Mosapride can significantly improve the clinical symptoms of patients with reflux esophagitis，the treatment effect is obvious，which is worth learning and promoting. 　　【Key words】 Reflux esophagitis； Lansoprazole； Mosapride； Therapeutic effect 　　First-author’s address：The People’s Hospital of Beiliu，B