精神残疾程度与精神分裂症患者认知功能和阳性症状的相关性分析.docVIP

精神残疾程度与精神分裂症患者认知功能和阳性症状的相关性分析 　　摘 要 目的：探讨精神残疾程度与精神分裂症患者认知功能和阳性症状的关系。方法：选取2014年1月-2015年1月期间我院精神病科门诊部就诊的精神分裂症患者126例作为研究组（其中轻度残疾亚组67例，中度残疾亚组25例，重度残疾亚组34例），同期选取我院健康体检者125例作为对照组，比较认知功能测试和PANSS阳性症状评分的差异。结果：研究组RBANS认知功能各维度评分均明显低于对照组，研究组非持续错误率、持续性应答数、概念化水平和完成分类指标明显低于对照组，持续错误数明显高于对照组，研究组WHO-DAS Ⅱ评分和PANSS阳性症状评分均明显高于对照组。轻度残疾亚组RBANS评分明显高于中度残疾亚组和重度残疾亚组，中度残疾亚组RBANS评分明显高于重度残疾亚组；轻度残疾亚组PANSS阳性症状评分明显低于中度残疾亚组和重度残疾亚组，中度残疾亚组PANSS阳性症状评分明显低于重度残疾亚组。差异均具有统计学意义。结论：不同精神残疾程度的精神分裂症患者认知功能和PANSS阳性症状评分差异显著，精神分裂症患者认知功能及其阳性症状与精神残疾程度紧密相关。 　　关键词 精神残疾 精神分裂症 认知功能 阳性症状 　　中图分类号：R749.3 文献标识码：A 文章编号：1006-1533（2015）17-0047-04 　　The analysis of the relationship of the degree of mental disability and the cognitive function and positive symptoms of patients with schizophrenia* 　　WANG Fei**， ZHU Zhengren， HUANG Ping 　　（The Third People’s Hospital of Ganzhou City， Jiangxi Province， Ganzhou 341000， China） 　　ABSTRACT Objective： To investigate the relationship between the degree of mental disability and the cognitive function and positive symptoms of patients with schizophrenia. Methods： One hundred and twenty-six cases of patients with schizophrenia in our hospital from Jan.， 2014 to Jan.， 2015 were selected as a study group， which was subdivided a mild， moderate or severe disability subgroup with 67， 25 and 34 cases each. One hundred and twenty-five cases of healthy persons participating in physical examination in our hospital were selected as a control group. The differences of cognitive function and PANSS positive symptom score were compared. Results： The RBANS dimensions scores and the indexes of non continuous error rate， sustained response， conceptual level and completed classification of the study group were significantly lower than those of the control group， and the persistent error and WHO-DAS score and PANSS positive symptoms score of the study group were significantly higher than those of the control group. An increment trend was presented in RBANS score while a decrement trend in PANSS posit