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For example, in spring and summer when the weather changes from warm to hot and yang qi ascends, the interstices 腠理 of the body become looser. During this period, even for external contraction of wind-cold, pungent-warm dispersing drugs, such as Ma Huang (Herba Ephedrae) and Gui Zhi (Ramulus Cinnamomi), should be used cautiously so as not to impair qi and yin due to excessive dispersion; in autumn and winter when the weather turns cold from cool and yin becomes preponderant with decline of yang, the interstices become tighter and yang qi retreats interiorly. So drugs of cool or cold nature, such as Shi Gao (Gypsum Fibrosum) and Bo He(Herba Menthae), should be used cautiously to avoid impairment of yang qi. 2. Treatment in accordance with local conditions It refers to that therapeutic principles should be determined according to features of geographical environment. Individuals in various geographic environments differ in constitutional features and pathological changes due to diverse climatic conditions and living habits. Accordingly, treatment and prescription should be suited to local conditions as well. For example, in the northwestern highlands of China, it is cold and dry, with scanty rainfall. So wind-cold and dryness are commonly seen and usually treated by pungent-moistening formula, while cold-cool-dry formula should be used with great care. In the southeastern coastal lowlands of China, it is hot and damp, with plentiful rainfall. So damp-heat is commonly seen and should be treated by heat clearing and damp-resolving drugs, while damp-inducing drugs of warm or hot nature should be used cautiously. 3. Treatment in accordance with patients individuality It refers to that therapeutic principles should be determined according to features of patients age, sex, constitutions, living habits and occupations. A. Age Individuals of different ages are characterized by different physiological functions and pathological changes. Due to deficient qi and blood as well a
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