The Impact of Zinc Supplementation during Diarrhoeal Illness in.pptVIP

Where are we now?WHO’s Perspective Recent developments in the clinical management of acute diarrhoea Meta-analysis of unscheduled intravenous infusion among children randomized to reduced osmolarity and standard WHO rehydration solution Meta-analysis of stool output among children randomized to reduced osmolarity and standard WHO rehydration solution Meta-analysis of vomiting among children randomized to reduced osmolarity and standard WHO rehydration solution CONCLUSION 1 Trials on the Therapeutic Effect of Zinc on Acute Diarrhea Countries: Bangladesh 4 , Brazil, India 6 , Indonesia, Nepal Age groups: 1-60 months Dose of zinc: 5 to 40 mg/day 1 to 4 RDA Total number of children: zinc 4965 control 4351 Effect of Zinc Supplementation on Duration of Acute Diarrhoea/Time to Recovery Effect of Zinc Supplementation on Duration of Episodes Lasting More than 7 Days Therapeutic Effects of Zinc Supplementation on Acute Diarrheal Severity 1 Therapeutic Effects of Zinc Supplementation on Acute Diarrheal Severity 2 CONCLUSIONS 2 Zinc supplementation given at a dose of about 2 RDAs per day 10-20 mg for 10-14 days, is efficacious in reducing the severity of diarrhoea and the duration of the episode significantly. WHO/UNICEF JOINT STATEMENT Clinical Management of Acute Diarrhoea Recommendations for Mothers and Other Caregivers Prevent dehydration through the early administration of increased amounts of appropriate fluids available in the home, and ORS solution, if on hand Continue feeding or increase breastfeeding during, and increase all feeding after the episode Recognize the signs of dehydration and take the child to a health-care provider for ORS or intravenous electrolyte solution, as well as familiarize themselves with other symptoms requiring medical treatment e.g., bloody diarrhoea Provide infants with 20 mg per day of zinc supplementation for 10–14 days 10 mg per day for infants under six months old Recommendations for Health-Care Work