组织再生用压电材料.ppt

5.2. Piezopolymers Discovery of the piezoelectricity of polyvinylidene fluoride (PVDF) by Kawai made this polymer a candidate substitute for PZT. Due to its flexibility and nontoxicity, PVDF has been used for a variety of biomedical pplications, from tissue engineering scaffolds to implantable self-powered devices. Piezoelectric materials for tissue regeneration: A review Speaker：Zhangquan Team members: Sihewei and Fengtiantian CONTENTS 1. Introduction 2. Piezoelectricity in biological tissues 3. Piezoelectricity and streaming potential 4. Cellular response to electrical stimulation 5. Piezoelectric materials in tissue regeneration applications 6. Conclusion 1. Introduction Piezoelectric materials are smart materials that can generate electrical activity in response to minute deformations. First discovered by Pierre and Jacques Curie in 1880, deformation results in the asymmetric shift of ions or charges in piezoelectric materials, which induces a change in the electric polarization, and thus electricity is generated. Piezoelectric materials are widely used in various electronic applications such as transducers, sensors and actuators. For biomedical applications, piezoelectric materials allow for the delivery of an electrical stimulus without the need for an external power source. As a scaffold for tissue engineering, there is growing interest in piezoelectric materials due to their potential of providing electrical stimulation to cells to promote tissue formation. In this review, the author cover the discovery of piezoelectricity in biological tissues,and summarizes their potential as a promising scaffold in the tissue engineering field. 2. Piezoelectricity in biological tissues In 1940, Martin noticed the first demonstration of biological piezoelectricity, when he detected electric potentials from a bundle of wool encapsulated in shellac while compressed by two brass plates. The main constituent of mammalian hai