太宁栓纳肛联合95%酒精纱布局部湿敷治疗放化疗后痔疮复发的疗效观察.docVIP

太宁栓纳肛联合95%酒精纱布局部湿敷治疗放化疗后痔疮复发的疗效观察 　　摘要：目的 探讨太宁栓（复方角菜酸酯栓）纳肛联合95%酒精纱布局部湿敷治疗放化疗后痔疮复发患者的疗效。方法 将我科88例放化疗后痔疮复发的肿瘤患者按照随机分组原则，分为试验组和对照组，每组各44例。试验组患者采用太宁栓纳肛联合95%酒精纱布局部湿敷治疗痔疮，对照组患者仅以95%酒精纱布局部湿敷治疗痔疮，同时由责任护士进行针对性护理；治疗1w后，比较两组患者疼痛、出血及疗效情况。结果 对照组患者总的有效率为77.3%，试验组总有效率为95.5%，试验组明显高于对照组，P0.05，两组比较差异具有统计学意义；干预后试验组患者的痔疮疼痛评分状况较对照组明显降低，两组比较，P0.05，差异具有统计学意义。结论 太宁栓纳肛联合95%酒精纱布局部湿敷治疗放化疗后痔疮复发能有效减轻肿瘤患者痛苦，增加患者痔疮治疗效果，提高患者的生活质量。在临床痔疮治疗中有指导意义。 　　关键词：太宁栓；酒精；痔疮 　　Abstract：Objective To explore the curative effects of Titanoreine Suppository with 95%alcohol on hemorrhoids patients with recurrence after Radiation and chemotherapy.Methods 88 hemorrhoids patients with recurrence after Radiation and chemotherapy were equally randomized into the observation group and control group.The observation group was treated with Titanoreine Suppository with 95% alcohol wet packing .The patients in the control group were treated with 95%alcohol.After a week of treatment，the pain in the patients and the curative effects were compared between the two groups. Results The total effective rates of the observation group and the control group were 95.9%and 77.3%，respectively（P0.05）.The pains in the patients of the observation group were significantly relieved compared to those of the control group（P0.05）.Conclusion Titanoreine Suppository combined with 95%alcohol together with pertinent nursing intervention is effective in the treatment of hemorrhoids patients with recurrence after Radiation and chemotherapy and reducing maternal pains. Can increase hemorrhoids treatment effect， improve the patients quality of life. As a guidance in the clinical hemorrhoids treatment. 　　Key words：Titanoreine suppository；Alcohol；Hemorrhoids 　　放化疗作为晚期恶性肿瘤不能手术患者的主要治疗手段之一，在肿瘤学临床中应用广泛。近些年来放化疗技术取得了巨大的进展，随着调强适形放射治疗技术以及靶向治疗药物应用于临床治疗，精确放疗与化疗减轻了放化疗的副反应，让患者获益。但是由于其放射性的特质，其毒副作用及不良反应发生率仍然居高不下。放射治疗可以损害胃肠道肠道黏膜；化疗药物可以直接干扰肠壁细胞的分裂， 导致肠壁细胞出现坏死，继而肠壁广泛的炎症发生， 造成肠壁吸收与分泌细胞数量之间的动态平衡发生迅速变化，引起肠细胞过度分泌消化液， 同时吸收面积减少而形成腹泻。加之肿瘤患者常常伴有恶病质，本身胃肠道防御功能就弱，经常引起呕吐、纳差、腹泻等