不同水质对小鼠脏器系数及血糖影响的研究.docVIP

不同水质对小鼠脏器系数及血糖影响的研究 　　[摘要] 目的 初步探讨不同饮用水对小鼠脏器系数及血糖水平的影响。 方法 分别测定纯净水、自来水、净化水、高偏硅酸天然矿泉水的偏硅酸含量。将80只ICR小鼠随机分为4组，每组各20只，雌雄各半，分别用纯净水（对照组）、自来水、净化水和矿泉水喂养，90 d后眼球取血，测定空腹血糖值及小鼠体重、脏器系数。 结果 4种饮用水的偏硅酸含量差异有统计学意义（P0.05），含量高低依次为纯净水净化水自来水矿泉水。与纯净水组比较，净化水组的小鼠心脏系数明显降低（P0.05）；矿泉水组雌性小鼠的空腹血糖水平也明显降低（P0.05）。 结论 不同水质可能对小鼠心脏系数及雌性小鼠血糖代谢有影响。 　　[关键词] 水；偏硅酸；血糖；脏器系数 　　[中图分类号] R332 [文献标识码] A [文章编号] 1674-4721（2014）08（a）-0017-03 　　Effect of different water quality on organ coefficent and blood glucose in mice 　　CHEN Rong-he1 ZHANG Tong-nian2 RUAN Guo-hong1 　　1.Department of Health Inspection and Quarantine，Fujian Medical University，Fuzhou 350108，China；2.Runhe Mineral Water Co. Ltd.，Fuzhou 350012，China 　　[Abstract] Objective To explore the effect of different drinking water on organ coefficent and blood glucose in mice. Methods Metasilicic acid content was measured in the pure water，tap water，filtered tap-water and high metasilicate mineral water respectively.80 ICR mice （half male and half female） were randomly divided into the four groups and fed with pure water （the control group），tap water，filtered tap-water and mineral water respectively.After 90 days， blood samples were taken from the eyeballs of mice. Then the fasting blood glucose，body weight and organ coefficient were analyzed. Results Metasilicic acid content of four kinds of drinking water had a statistical difference （P0.05）， which were pure waterfiltered tap-watertap watermineral water.Compared with the control group，a significant decline in cardiac coefficient of mice was observed in filtered tap-water group （P0.05），and the same significant decline in fasting blood glucose of female mice was observed in the mineral water group （P0.05）. Conclusion Different water quality may cause biological effects on cardiac coefficient of mice and glucose metabolism in female mice. 　　[Key words] Water；Metasilicic acid；Blood glucose；Organ coefficient 　　随着社会经济的发展和人们生活水平的提高，目前人们对饮用水的选择日益多样化。除普通自来水外，市场上各种各样的新型饮用水正因其良好的卫生质量及保健功效，被越来越多的人选择作为日常饮水的