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OVERVIEW OF SOLID ORGAN TRANSPLANTATION实体器官移植概述
Common Causes of Kidney Failure Diabetes Type I II (diabetic nephropathy) Hypertension Hereditary Polycystic Kidney Disease (PCKD) Auto-Immune Primary Glomerulonephritis Systemic Lupus Erythematosus (SLE) Renal Cell Carcinoma (RCC) Renal Artery Stenosis / Renal Vein Thrombosis Urologic Reflux Nephropathy Stones Frequent chronic UTI’s UNOS Wait List As of 4/3/09 - US - 109,294 waiting for organ transplant US - 83,913 waiting for kidneys WI - 1,538 awaiting transplant WI - 1,115 waiting for kidneys UWHC – 724 on transplant wait lists UWHC – 495 waiting for kidneys Blood Type Compatibility The Operation Transplanted kidney’s artery vein attached to recipient’s iliacs An incision is made in bladder ureter is attached UW Health Transplant Experience 1966 kidney transplant program established, including deceased live donor transplants 1997 OPO ranked most effective in the U.S. 2000 laparoscopic kidney donor nephrectomy began 2003 1st humanitarian live-donor kidney transplant 1st paired exchange transplant 2004 desensitization program started donor mentor program developed Why is Living Donor Transplant Recommended? Longer Kidney Survival 8-12 years for deceased donor transplant 12-20 years for living donor transplant Reduce Need for Future Re-Transplant Shorter Wait Times for Transplant Surgery Scheduled for Convenience Healthy Donor Kidney Benefits of Living Donor Transplant (continued) Able to Return to Work Kidney Works Right Away May Be a Closer Genetic Match Lower Cost Increase Kidneys Available for Transplants Improve Quality of Life Why Don’t More Patients Get A Living Donor? Don’t have enough information Fearful for the donor’s safety Don’t understand the donor’s experience Can’t bring themselves to ask Waiting for someone to offer Don’t want family/friends to feel obligated Don’t want to be a burden Refuse to accept kidney from adult children Finding a Living Donor The donor’s health is the goal in the screening. A risky transplant does
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