Substances viewed through the lens of trauma Substance expectancies in women with PTSDSUD.pdfVIP
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Substances viewed through the lens of trauma Substance expectancies in women with PTSDSUD.pdf
e230
Abstracts / Drug and Alcohol Dependence 140 (2014) e169–e251
Correlates of impaired cognitive performance in cocaine- and opioid-dependent patients
Annie Umbricht, Miriam Mintzer, Olga Rass, G.E. Bigelow, Matthew W. Johnson, E.C. Strain, David A. Tompkins
Psychiatry, Johns Hopkins University, Baltimore, MD, United States
Aims: There is evidence for cognitive impairment in individuals with substance use disorders. The purpose of this analysis was to identify speci?c demographic and clinical characteristics associated with poorer cognitive performance in individuals dually dependent on cocaine and opioids who were stabilized on methadone for ?ve weeks.
Methods: A correlational analysis (Spearman’s rho) was conducted between outcome measures from a cognitive assessment battery and demographic and clinical variables for 77 participants.
Results: The following variables were associated signi?cantly (p 0.05) with poorer cognitive performance: higher age (worse psychomotor coordination, focused and divided attention, executive function, working memory, episodic memory), lower education (worse executive function), lower IQ as measured by Shipley’s Institute of Living Scale (worse focused attention, executive function, working memory, episodic memory), greater lifetime and 30-day poly-drug use as assessed by the Addiction Severity Index (worse executive function), higher cocaine use severity ratings (worse focused and divided attention), more smoking urges as assessed by the Questionnaire on Smoking Urges (worse working memory, episodic memory), greater anxiety as measured by the State Trait Anxiety Inventory (worse working memory, episodic memory), greater PTSD Symptom Scale score (worse focused and divided attention, episodic memory), higher pain ratings on a visual analog scale (worse working memory, episodic memory), and greater impulsivity on the Barrett Impulsiveness Scale (worse focused and divided attention, working memory, episodic memory).
Conclusions: While
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