IdiotsguidetoGeneralLinearModelfMRI.pptVIP

Idiots guide to...General Linear Model fMRI Elliot Freeman, ICN. General Linear Model fMRI How does GLM apply to fMRI experiments? Y = X . β + ε Observed = Predictors * Parameters + Error BOLD = Design Matrix * Betas + Error Observed data Univariate analysis Each voxel considered as independent observation Analysis of individual voxels over time, not groups over space SPM would still work on an Amoeba! Continuous predictors Binary predictors Parameters error β: slope of line relating X to Y ‘how much of X is needed to approximate Y?’ the b