Clinical application of allogeneic bone transplantation research.docVIP

 PAGE \* MERGEFORMAT 17 Clinical application of allogeneic bone transplantation research Author: Cao Bo Cui Wei Wang Jun Wang Peng Keywords: allogeneic bone; bone transplantation; bone bank; Review Trauma, infection and bone tumors and other causes of massive bone, joint defects is the field of orthopedics and surgical reconstruction is more pervasive and intractable problems, although the availability of autologous bone graft immune response, rapid healing characteristics, but the source is limited. Prosthesis, been able to repair damaged parts and restore some functions, but the lack of biological activity. A rich source of allograft bone, without shape, size limits, and have biological activity, has good clinical application prospect. Since 1941, put forward the concept of bone bank [1] has been allogeneic bone graft preservation techniques with the development and establishment of foreign and domestic bank bone, the clinical application of allogeneic bone growing, has made more mature experience. In this paper, allogeneic bone preparation, preservation, healing mechanism and clinical application are reviewed. An allogeneic bone preparation and preservation 1.1 allogeneic bone derived mostly from infectious disease-free, non-malignant, non-endocrine disease, non-metabolic diseases, non-toxic and radioactive substances with a long history of exposure to less than 4 ~ 8h fresh bones, traumatic amputation of bone surgical resection of the femoral head, ribs, patella, and other parts of the fresh bone and induction of labor DI 6 ~ September mother and child health, fetal bone as a bone bank bone reserves. Taboo collected from cancer, infectious diseases, bacterial infections, bone, blood, bone tissue patients. According to the graft were divided into allogeneic bone transplantation, allogeneic cartilage transplants, allogeneic bone and joint transplantation. 1.2 allogeneic bone preservation in the current major applicatio