Clinical application of anti-arrhythmic drugs.docVIP

 PAGE \* MERGEFORMAT 8 Clinical application of anti-arrhythmic drugs Abstract: Objective To study the effects of antiarrhythmic drug therapy, safety and the choice of antiarrhythmic drugs. Methods in our hospital from 2006 to 2009 cases of patients with drug treatment, research and clinical applications of its efficacy. Conclusions in the application of anti- arrhythmic drugs, be sure to follow the doctor’s advice for treatment. Keywords:: clinical application of antiarrhythmic drug summary Very different clinical manifestations of arrhythmias, and some arrhythmias without clinical significance, while others affect the health and life-threatening. So they have to consider the need for drug treatment of this arrhythmia, additional therapy, which drug to choose the best choice. to the selected well-known drug pharmacokinetics, pharmacodynamics and its influence on cardiac electrophysiology. Almost all anti-arrhythmic drugs, are inhibited to varying degrees of self-regulation of the heart, conduction and cardiac contractile function, almost all antiarrhythmic drugs have proarrhythmic side effects. So far, these drugs on cardiomyopathy, serious heart disease for a more reasonable state of clinical data was not enough, when cardiac dysfunction, myocardial ischemia, physiological and biochemical metabolic disorder, its anti-arrhythmic drugs impact, there must be sufficient attention and understanding. through practice, gradually formed his own medicine physician experience with different programs in different cases, ie, the implementation of the principle of individual drugs. Now some of the commonly used anti-arrhythmic drugs for clinical application and usage summary: 1. Quinidine [Pharmacological characteristics] Quinidine is a typical I a class of drugs, mainly inhibit cell membrane sodium channels, the sodium ions flow down, inhibit cardiac self-discipline. Quinidine inhibition of muscarinic receptors by vagal blocking effec