Clinical application of PET imaging instrument of the breadth and limitations of_0.docVIP

 PAGE \* MERGEFORMAT 13 Clinical application of PET imaging instrument of the breadth and limitations of [Keywords:] PET imaging device; type, clinical application In recent years, undertaken a wide range of clinical PET imaging, from the original only a few research-based medical center, quickly spread across the country in all major General Hospital, PET is playing an increasingly important role. PET-CT can not only reflect the human body anatomical changes, more importantly, the body functions can provide metabolic information from the molecular level reveal the disease pathogenesis and treatment effect, is a clinical diagnosis of heart and brain diseases and tumors of the important means. now its clinical application are described below. 1 PET-CT in the clinical application of tumor 1.1 Diagnosis and staging of tumor The prevalence of tumor cells in rapidly proliferating, increasing the cell membrane and intracellular glucose transporter enzyme activity increased phosphorylation of the biological characteristics, making the tumor cells significantly increased metabolism in the glycolysis. Thus, the tumor is the most popular electronic imaging the 18F labeled fluorodeoxyglucose (18F-FDG.18F-FDG can enter the body’s metabolism of almost all types of cancer imaging, is a spectrum of tumor tracer .18 F-FDG uptake within the cells and the intracellular level of glucose the level of metabolism was positively correlated, in general, the higher the degree of tumor malignancy, FDG uptake is more obvious. use of tumor cells “capture” FDG features the ability to increase not only early detection and identification of malignant primary tumor location, size, can also assess the degree of malignancy, in addition, the body 18F-FDG PET-CT imaging for lymph node and distant metastasis has a high detection rate, can improve the accuracy of staging [1]. 1.2 The monitoring of tumor recurrence and metastasis After treatment, CT detected tumor activity in tu