Clinical observation of methylprednisolone treatment of Kawasaki disease.docVIP

 PAGE \* MERGEFORMAT 10 Clinical observation of methylprednisolone treatment of Kawasaki disease [Abstract] Objective Kawasaki disease (KD) in children with acute inflammation of corticosteroids (methylprednisolone) patients. Methods The subjects were from January 2002 to September 2006 patients were treated 68 cases of KD. According to a splash The use of nylon or not, were randomly divided into two groups. the control group (35 cases) with intravenous immunoglobulin (IVIG) [1 g / (kg · d), qd for 2 days] + aspirin (ASA) [30 ~ 50 mg / (kg · d)]; treatment group (33 cases) with methylprednisolone [20 ~ 30 mg / (kg · d), use 3 days] + intravenous gamma globulin [1 g / (kg · d) , once a 2 days] + ASA [30 ~ 50 mg / (kg · d)]. and then two groups of acute inflammation on the control and coronary artery disease (CAL) compared the situation. the treatment group and control group in the body temperature, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), platelet (PLT) restored the normal time difference was significant (P lt;0.05). up for 3 months, CAL number of cases: the treatment group 1 patients (3%), 7 cases were (17.1%), significant difference between the two groups (P lt;0.05). Conclusions Treatment of acute Kawasaki disease glucocorticoids can shorten the course, reduce the occurrence of CAL. [Keywords:] Kawasaki disease; poured nylon; of aspirin Kawasaki disease is a major in pre-school children under 5 years old and infants with acute febrile rash disease, since the rich do Japanese doctors in 1967 Kawasaki first described the disease since the disease has most countries in the world Regional news. in the world the incidence increased year by year. In developed countries or regions, KD coronary artery lesions caused by (CAL) has replaced rheumatic fever as children of the most common acquired one of major cause of heart disease [1] intravenous gamma globulin prevention of KD patients was considered to be an ideal drug CAL. But recent r