Electric pulse stimulation in vitro in diabetic rat urinary bladder function in.docVIP

 PAGE \* MERGEFORMAT 20 Electric pulse stimulation in vitro in diabetic rat urinary bladder function in Authors: Song Tao, Wei-Qing, Deng Xiang Lei, easily detached, Wang Huan, Lu Lu 【Abstract】 Objective: To investigate the in vitro electrical stimulation in diabetic rat urinary bladder function. Methods: SD rats were randomly divided into normal control group, diabetic control group and diabetic group of electrical stimulation three groups of 10, the latter two groups made diabetic rat bladder model. After 10 weeks, electrical stimulation to the external electrical stimulation therapy, stimulation parameters: intensity of 31V, density of 31Hz, the other two groups were no electrical stimulation. Observed after 3 weeks continuous treatment group as compared with urodynamic changes and functional changes in detrusor muscle strips. Results: The diabetic rats after 10 weeks of modeling in vitro electrical stimulation to exert its efforts in strengthening the bladder contraction, residual urine than (R%) decrease in urinary bladder threshold capacity to reduce the differences were statistically significant. Conclusion: In vitro electrical stimulation can improve diabetic bladder detrusor contractility and bladder sensory function. Keywords: in vitro electrical pulse stimulation; diabetic bladder; urodynamics; rat Diabetic bladder disease (diabetic cystopathy, DCP) belongs to neuropathic vesicourethral dysfunction. As diabetes mellitus (DM) due to complications of urinary system and its incidence accounts for about 50% of patients with DM [1], and its specific disease mechanism is currently not fully understood. In recent years, studies have shown that, in addition to its own myogenic detrusor dysfunction, bladder control peripheral neuropathy is one of the mechanisms of its pathogenesis. At present a variety of electrical stimulation of the body has been gradually applied to the treatment of neurogenic bladder dysfunction [2], but the use o