Elemene dilute the impact of lung cancer cell apoptosis.docVIP

 PAGE \* MERGEFORMAT 6 Elemene dilute the impact of lung cancer cell apoptosis Author: Xu Yan Dan Lang Dan Li Yuhong [Abstract] Objective: To study the elemene dilute the role of apoptosis in lung cancer cells. Methods: MTT method and Annexin V / PI assay elemene and cisplatin diluted A549 lung cancer cell lines acting on the toxicity and apoptosis, relatively elemene and cisplatin-induced apoptosis in dilute differences. Results: Lam Heung-toxic concentration of rare cells in half of the 102.21 μ g/m1, elemene dilute with cell toxicity, and dose-effect relationship, but was weaker than cisplatin; elemene and cisplatin can dilute the promotion of lung cancer A549 cells, both of without a significant difference. Conclusion: Lam Heung Lean can effectively induce apoptosis in lung cancer cells, guiding significance for clinical medicine. [Keywords:] elemene rare; lung cancer; apoptosis The production of tumor cell apoptosis, growth rate and prognosis play a very important role. Through the direct regulation of apoptosis of tumor cells growth. Lung cancer is one of the high incidence of tumors, a serious threat to human life. Apoptosis in the maintenance of environmental stability in the body play an important role in lung cancer cells induced apoptosis in lung cancer treatment has now become a research direction. Induced apoptosis in lung cancer cells that may contain the occurrence of lung cancer and development. Studies have shown that cisplatin can induce human leukocyte apoptosis in HL  60 cells, showing a clear dose-time-dependent relationship; and the low-dose cisplatin on the role of radiation with sensitizing, radiation-induced apoptosis is also a mechanism of action of radiotherapy 1 [1]. Cis-platinum, adriamycin, etc. and a variety of radiation-induced tumor cell apoptosis in cancer therapy research has become a hot spot, but the thin elemene induced apoptosis in lung cancer cells less. We have to use cell culture techniques, using MTT method and A