Embryonic stem cell research in ophthalmology.docVIP

 PAGE \* MERGEFORMAT 24 Embryonic stem cell research in ophthalmology Abstract Embryonic stem cells are a class of self-renewal and high proliferative capacity of totipotent cells. Since 1998, human embryonic stem cells cultured in vitro successfully, scholars at home and abroad a great deal of research, a growing number of studies have shown that the embryonic stem cells as donor cells for corneal transplantation and retinal transplants may be added that damage cells, reconstruction Eye the table and restore retinal function, to a number of refractory ocular surface and the treatment of retinal diseases, provides a new way. In this paper, embryonic stem cell transplantation in ophthalmology application prospects are reviewed. Keywords: embryonic stem cell transplantation for cell therapy 0 Introduction In 1998, when Thomson et al [1] First isolated from embryos cultured in human embryonic stem cells, and subsequently found it to differentiate into almost all the cells in the body after the stem cells into human beings in the 21st century, one of the great scientific and technological achievements, people stem cells injected great enthusiasm. Stem cells are a class of self-renewing, highly proliferative and multi-differentiation potential of cells, mainly divided into embryonic stem cells and adult stem cells. Embryonic stem cells (embryonic stem cells, ESCs) are derived from human or animal embryonic cell mass or primitive within the genital ridge of a pluripotent cell, almost all of the adult tissue differentiation. Most of blinding eye disease, such as severe ocular surface disease, glaucoma, retinitis pigmentosa, etc., there is irreversible cell damage and degeneration of the pathological process, therefore, the application ESCs as a cell donor transplant therapy might complement damage cells , reconstruction and restoration of ocular retinal function, patients of such diseases, restoring hope. This paper will ESCs in ophthalmolo