Emphasis on quality of life in patients with major depressive disorder and its treatment of the relationship between fluoxetine.docVIP

 PAGE \* MERGEFORMAT 3 Emphasis on quality of life in patients with major depressive disorder and its treatment of the relationship between fluoxetine Author: Wang Qiong Xu Yong Peng Ju Italian Sun Junwei Sun Ning Zhang Kerang [Abstract] Objective To investigate the survival of patients with major depressive disorder with fluoxetine treatment quality and its relationship. Methods This study used case-control study method, measurement of 17 Hamilton Depression Rating Scale (HAMD), simple health questionnaire (SF-36) and adverse reactions Scale (TESS). Patients were the use of fluoxetine in the treatment for 6 weeks before and after treatment were assessed for the above-mentioned scale. Were used to compare the number of t test and ANOVA analysis, fluoxetine clinical efficacy and quality of life improvements for Pearson correlation. Results (1) in case group (before treatment and after treatment) Quality of life was significantly lower than the control group (P amp;lt;0.01). (2), compared with those before treatment, after 6 weeks treatment in case group SF-36 all factors were significantly higher (P amp;lt;0.01 ~ 0.05). (3) HAMD reduction rate and quality of life was a certain positive correlation (P amp;lt;0.01 ~ 0.05). At the same time, adverse drug reactions to the quality of life also have a certain influence, there are adverse reactions Groups physiological function (PF) and energy (VT) factors were significantly lower than those without adverse reaction group (P ≤ 0.05). Conclusions Patients with major depressive disorder significantly decreased quality of life, fluoxetine within 6 weeks can significantly improve major depression in patients quality of life, but have not yet returned to normal population levels. Improvements in the quality of life in patients with clinical efficacy was some positive correlation, but also by the adverse drug reactions, and other factors. [Keywords:] emphasis on quality of life of fluoxetine in major depressive disorder