Endurance exercise on leptin receptors in liver of high fat diet IGF1 and IGFBP3 of.docVIP

 PAGE \* MERGEFORMAT 10 Endurance exercise on leptin receptors in liver of high fat diet IGF1 and IGFBP3 of [Abstract] Objective To investigate the endurance exercise on the high fat diet rat liver insulin-like growth factor 1 (IGF 1), insulin-like growth factor binding protein 3 (IGFBP 3) and leptin receptor in rats. Methods 20 rats were randomly divided into the quiet group (H group) and the endurance training group (R group), n = 10, training, 8 w, by Bedford training program, endurance training is equivalent to 65% VO2max, 24 h after the last training in a quiet state of the rats The following were killed, and liver. by enzyme-linked immunosorbent assay test (quantitative) were determined in liver IGF 1, IGFBP 3 and leptin receptor content. Results Group IGF 1 R protein content was significantly higher than the H group (P lt;0.05), R group of IGFBP 3 protein content was significantly higher than that of H group (P lt;0.05), IGFBP 3/IGF 1 ratio of the two groups no significant difference, R group leptin receptor levels are significantly higher than the H group (P lt;0.01). Conclusion endurance exercise can promote high-fat diet rats IGF 1, IGFBP 3 and leptin receptor expression is a very effective treatment modality for the promotion of health of the body have a certain significance. [Keywords:] endurance exercise, high fat diet, IGF 1, IGFBP 3, leptin receptor [Abstract] Objective To investigate the effects of endurance exercise on insulin growth factor 1 (IGF 1) and insulin growth factor binding protein 3 (IGFBP 3) and leptin receptor in hyperlipid diet rats’liver. Methods 20 male SD rats were randomly divided into quietness group (H) and endurance exercise group (R) (n = 10) .8 weeks training was carried. Bedford’s exercise program was adopted.Exercise intensity of R was seemly equal to 65% VO2max. After the last training 24 h , the rats were killed and liver was taken out. The contents of IGF 1, IGFBP 3 and leptin receptor were measured by ELISA