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Leishmaniasis
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Leishmaniasis
Abstract: Leishmaniasis is caused by Leishmania zoonotic diseases that can cause human skin and visceral leishmaniasis. Introduction leishmaniasis pathogenesis, host-parasite interactions, clinical manifestations and treatment of prevention.
Leishmaniasis is a zoonotic disease caused by Leishmania in the arthropod and mammalian transmission. The disease occurs in more than 80 countries estimated to number more than 15 million patients, new cases each year for 40 million. For HIV infection, the Leishmania parasite may be a condition of disease-causing parasites.
Pathogens Categories
Leishmania are intracellular parasitic protozoa belonging to Trypanosoma Section Kinetoplastida. Of this genus can be infected with many kinds of mammals. Leishmania classification is one of the most common method for isozyme immunoelectrophoresis.
Morphology of Leishmania
Leishmania parasites for the heterogeneous lifetime requires two hosts. It has 3 different forms: amastin, the former flagella body paraflagellar body. Amastin more in vertebrate host cells, containing dynamic grana. The former Vice-flagellated flagellated body and body present in the sandfly gut and multi-media. Flagellar body before the media in the absence of invertebrates in the most common. Spindle-shaped, front-end has a flagellum. Paraflagellar body is the first two forms of transition.
Media
Sandfly is a recognized Leishmania transmission medium. Sandfly activity at night, through the bite of blood-sucking mammals to survive. Only blood-sucking female sandflies, which will help to lay eggs. Sandfly more common in the warm season. In the appropriate conditions, it’s life-cycle 41 ~ 58 days. Female can lay 100 or so, take 1 ~ 2 weeks hatched. Larvae need the right temperature, dark, and the organic and developmental maturity.
Life history of Leishmania
Sandfly bites infected spinal animals into the sandfly amastin body never changed for the for
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