Standardization of allergen-specific immunotherapy in children with asthma application security.docVIP

Standardization of allergen-specific immunotherapy in children with asthma application security.doc

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Standardization of allergen-specific immunotherapy in children with asthma application security

 PAGE \* MERGEFORMAT 27 Standardization of allergen-specific immunotherapy in children with asthma application security Keywords: Asthma Childhood asthma as a common chronic airway disease, its prevalence on the rise. Studies have shown that children allergic airway disease, mainly in the large number of allergens in the environment as the main cause. Specific immunotherapy (specific  immunotherapy, SIT) as a potentially change the natural course of allergic diseases due to treatment and after cessation of treatment with long-term protective effect of the therapy in children with asthma has become inhaled glucocorticoids (ICS ) and other symptomatic treatment with a promising important addition to treatment. SIT has been used since 1911, the clinical years, has over 90 years of history. Although this has done a lot of research, but its safety remains its clinical application in practice has drawn greater attention important issues. SIT security and a variety of factors related to whether the standardization of allergen which is an important factor. Therefore, WHO recommends the use of such high-quality standardized allergen vaccines, to reduce the SIT treatment the incidence of adverse reactions. Standardization of allergens in the country to carry out not more than pediatrics, the lack of long observation of the safety of the treatment reports, this article on the standardization of allergens in children with asthma application security are reviewed. A standardization of allergen vaccines The standardization of allergen vaccines in the 70s of last century had begun. According to WHO standards, the standardization of allergen vaccines should meet the following requirements: the composition of the best and consistent; different batches and manufacturers of vaccines among the major allergenic protein content of the same; the total allergenic potency of the same. The allergen vaccines usually contain antigenic substances and potentially a

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