达英_35联合二甲双胍治疗多囊卵巢综合征临床效果观察_肖青.pdfVIP

2010 18 3 # 89# - 35 , , (广州市妇女儿童医疗中心, 510180) : 目的 探讨达英 - 35联合二甲双胍治疗多囊卵巢综合征的临 效果方法 将 60例多囊卵巢综合症患者随 机分为 3组, 分别予达英 - 35二甲双胍达英- 35联合二甲双胍治疗 3 个周期, 观察比较各项指标的变化结果 三组 患者治疗后与治疗前比较, 在 BM IWHR 方面无明显差异; 达英- 35 组治疗后 TLHDH EAS 明显降低及 SHBG 显著升 高 ( P 0105) ; 二甲双胍组治疗后TTCTGFBGFINS 明显降低及 SHBG 明显升高 ( P 01 05); 联合用药组治疗后 TLHDHEASTGFBGFINS均显著降低, SH BG 水平显著升高 ( P 0105)结论 达英- 35与二甲双胍联合应用 对多囊卵巢综合症具有更加全面的治疗效果 : 多囊卵巢综合征; 达英 - 35; 二甲双胍 : R7111 75 : B : 1006- 953 ( 2010) 03- 0089- 02 C lin ical analy sis on the effect of D iane- 35 com b in ed w ith m etform in in treatm en t of poly cy stic ovary syndrom e 1X IA O Q ing, G UON G Yong, LI U Yan1 ( Guangzhou Wom en and Ch ildrencs M edical C en er, Guangzhou 510180, P1R1Ch ina) A bstrac t: Objective: To evaluate the efficacy of D iane- 35 comb ined w ith m etform in for treating polycystic ovary syndrom e (P- COS) 1 M ethods: The 60 cases of polycystic ovary syndrom e w ere random ly d ivided into 3 groups1 Each group w as respectively re- ceived treatm en tw ith D iane- 35, m etform in, D iane- 35 com binedw ith m etform in1 And com pared the changes of the ind icators after 3 m onths1 Results: The 3 groups after treatment compared w ith before treatm en t, there was no s ignificant difference about the BM I and WHR1 The D iane- 35 group had significantly decreased in T, LH and DHEAS, and sign ificantly increased SH BG after treatm ent ( P 0105) 1 Them etform in group had s ignificantly decreased in T, TC, TG, FBG, FINS and sign ificantly increased in SHBG af- ter treatm ent ( P 01 05) 1 The D iane- 35 com bined w ith m etform in group had sign ificantly decreased in T, LH, DHEAS, TG, FBG, FINS and sign ifican tly increased in SH BG after treatm ent ( P 01 05) 1 Conclusions: TheD iane- 35 comb inedw ith m etform-