An Improved Synthesis of Some 5-Substituted Indolizines Using Regiospecific Lithiation.docVIP

Molecules 2005, 10, 1074-1083 molecules ISSN 1420-3049 An Improved Synthesis of Some 5-Substituted Indolizines Using Regiospecific Lithiation Alexey G. Kuznetsov, Alexander A. Bush, Viktor B. Rybakov and Eugene V. Babaev* Chemistry Department, Moscow State University, Moscow 119992, Russia. * Author to whom correspondence should be addressed; E-mail: babaev@org.chem.msu.su Received: 23 April 2005 / Published: 30 September 2005 Abstract: Various 2-substituted indolizines can be directly and selectively lithiated in the 5 position and subsequent reactions with different electrophiles