Analysis of IL-17+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response.docVIP
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AnalysisofIL-17cellsinfacetjointsofpatientswithspondyloarthritissuggeststhattheinnateimmunepathwaymightbeofgreaterrelevancethantheTh17-mediatedadaptiveimmuneresponse
Appeletal.ArthritisResearchTherapy2011,13:R95
/content/13/3/R95
RESEARCH ARTICLE
OpenAccess
AnalysisofIL-17+cellsinfacetjointsofpatients
withspondyloarthritissuggeststhattheinnate
immunepathwaymightbeofgreaterrelevance
thantheTh17-mediatedadaptiveimmune
response
HeinerAppel1*,RenéMaier1,PeihuaWu1,2,RebeccaScheer1,AxelHempfing3,RalphKayser4,AndreasThiel2,
AndreasRadbruch2,ChristophLoddenkemper5andJoachimSieper1,2
Abstract
Introduction:Inthisstudy,weanalysedthenumberofIL-17+ cellsinfacetjoints,intheperipheralblood(PB)and
synovialfluid(SF)ofspondyloarthritis(SpA)patientsandcomparedthesere
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