Analytical Challenges Determination of Tetrodotoxin in Human Urine and Plasma by LC-MSMS.docVIP

Mar. Drugs 2011, 9, 2291-2303; doi:10.3390/md9112291 OPEN ACCESS Marine Drugs ISSN 1660-3397 /journal/marinedrugs Review Analytical Challenges: Determination of Tetrodotoxin in Human Urine and Plasma by LC-MS/MS Kelvin Sze-Yin Leung 1,*, Bonnie Mei-Wah Fong 1,2 and Yeuk-Ki Tsoi 1 1 Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China; E-Mails: fongmw@.hk (B.M.-W.F.); sct1305b@ (Y.-K.T.) 2 Department of Pathology and Clinical Biochemistry, Queen Mary Hospital, Pokfulam Road, Hong Kong, China * Author to whom correspondence should be addressed; E-Mail: s9