Angioedema.docVIP

REVIEWARTICLE Angioedema AllenP.Kaplan ratory and gastrointestinal tracts, which typically lasts from Abstract: Angioedema can be caused by either mast cell de- granulationoractivationofthekallikrein-kinincascade.Intheformer case,angioedemacanbecausedbyallergicreactionscausedbyim- munoglobulin E (IgE)Ymediated hypersensitivity to foods or drugs that can also result in acute urticaria or a more generalized ana- phylacticreaction.Nonsteroidalanti-in?ammatorydrugs(cyclooxy- genase 1 inhibitors, in particular) may cause angioedema with or without urticaria, and leukotrienes may have a particular