Anti-PEG IgM Response against PEGylated Liposomes in Mice and Rats.docVIP

Pharmaceutics 2011, 3, 1-11; doi:10.3390/pharmaceutics3010001 OPEN ACCESS pharmaceutics ISSN 1999-4923 /journal/pharmaceutics Article Anti-PEG IgM Response against PEGylated Liposomes in Mice and Rats Masako Ichihara, Taro Shimizu, Ami Imoto, Yuki Hashiguchi, Yumi Uehara, Tatsuhiro Ishida * and Hiroshi Kiwada Department of Pharmacokinetics and Biopharmaceutics, Subdivision of Biopharmaceutical Science, Institute of Health Biosciences, The University of Tokushima, 1-78-1, Sho-machi, Tokushima 770-8505, Japan * Author to whom correspondence should be addressed; E-Mail: ishida@ph.tokushima-u