Anti-TNF therapy what have we learned in 12 years.docVIP

Kalden Arthritis Research Therapy 2011, 13(Suppl 1):S1 /content/13/S1/S1 INTRODUCTION Anti-TNF therapy: what have we learned in 12 years? Joachim R Kalden* Two decades ago, the available treatment options were inhibitors and disease-modifying antirheumatic drugs – not e? ective for many persons with rheumatoid arthritis speci? cally methotrexate – at an early stage of RA, (RA) and other in? ammatory rheumatic diseases. At this disease progression can be stopped or at least signi? - time RA patients had a signi? cantly decreased life e