Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases.docVIP

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2017-05-15 发布于上海
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Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases.doc

Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases

Ducourauetal.ArthritisResearchTherapy2011,13:R105 /content/13/3/R105 RESEARCH ARTICLE OpenAccess Antibodiestowardinfliximabareassociatedwith lowinfliximabconcentrationattreatment initiationandpoorinfliximabmaintenancein rheumaticdiseases EmilieDucourau1,2?,DenisMulleman1,2*?,GillesPaintaud1,3,DelphineChuMiowLin1,2,FrancineLauféron1,2, DavidTernant1,3,HervéWatier1,4 andPhilippeGoupille1,2 Abstract Introduction:Aproportionofpatientsreceivinginfliximabhaveantibodiestowardinfliximab(ATI),whichare associatedwithincreasedriskofinfusionreactionandreducedresponsetotreatment.Westudiedtheassociation

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Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases.docVIP