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Antibody engineering to develop new antirheumatic therapies
Available online /content/11/3/225
Review
Antibody engineering to develop new antirheumatic therapies
John D Isaacs
Wilson Horne Immunotherapy Centre and Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Framlington Place,
Newcastle-Upon-Tyne, NE2 4HH, UK
Corresponding author: John D Isaacs, j.d.isaacs@ncl.ac.uk
Published: 19 May 2009
Arthritis Research Therapy 2009, 11:225 (doi:10.1186/ar2594)
This article is online at /content/11/3/225
? 2009 BioMed Central Ltd
Abstract
the light chain two distinct domains, where a domain is a
discrete, fold
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