原创力文档Antimicrobial activity and mechanism of action of Nu-3, a protonated modified nucleotide.docVIP
- 6
- 0
- 约3.26万字
- 约 9页
- 2017-05-15 发布于上海
- 举报
Antimicrobial activity and mechanism of action of Nu-3, a protonated modified nucleotide
Caoetal.AnnalsofClinicalMicrobiologyandAntimicrobials2011,10:1
/content/10/1/1
RESEARCH
OpenAccess
Antimicrobialactivityandmechanismofactionof
Nu-3,aprotonatedmodifiednucleotide
ShanpingCao1,Lun-QuanSun2*,MingWang1*
Abstract
Background:“Nubiotics”aresyntheticoligonucleotidesandnucleotideswithnuclease-resistantbackbones,andare
fullyprotonatedforenhancedabilitytobetakenupbybacterialcells.Nu-3[butyl-phosphate-5’-thymidine-3’-
phosphate-butyl],oneofthefamilymembersofNubioticswasefficaciousinthetreatmentofburn-wound
infectionsbyPseudomonasaeruginosainmice.SubsequentstudiesrevealedthatNu-3hadafavo
您可能关注的文档
- Antiepileptic Drug Discovery and Development What Have We Learned and Where Are We Going.doc
- Anticoagulation in the Elderly.doc
- Antifactor Xa activity in critically ill patients receiving antithrombotic prophylaxis with standard dosages of certoparin a prospective, clinical study.doc
- Antifeedant Activity Evaluation of Withanolides from Jaborosa integrifolia.doc
- Antifouling Activity of Simple Synthetic Diterpenoids against Larvae of the Barnacle Balanus albicostatus Pilsbry.doc
- Antifilarial Lead Molecules Isolated from Trachyspermum ammi.doc
- Antifilaggrin antibodies in serum and synovial fluid samples of patients with rheumatoid arthritis show similar reactivity pattern towards citrulline containing peptides.doc
- Antifeedant Triterpenoids from the Seeds and Bark of Lansium domesticum cv Kokossan (Meliaceae).doc
- Antifungal Activity of Extracts and Prenylated Coumarins Isolated from Baccharis darwinii Hook & Arn. (Asteraceae).doc
- Antifungal Activity and Nail Permeation of Nail Lacquer Containing Piper regnellii (Miq.) C. CD. var. pallescens (C. DC.) Yunck (Piperaceae) Leave Extracts and Derivatives.doc
- 2026年山东省滨州市惠民县中考化学一模试卷（含答案）.pdf
- 2026年山东省济南市历城区中考化学二模试卷（含答案）.pdf
- 2026年山东省烟台市福山区中考化学模拟试卷（含答案）.pdf
- 2026年山东省临沂市郯城县中考化学一模（含答案）.pdf
- 2026年四川省德阳市中江县中考化学二诊试卷（含答案）.pdf
- 2026年四川省绵阳市梓潼县中考化学二模试卷（含答案）.pdf
- 2026年新疆乌鲁木齐市沙依巴克区中考化学适应性试卷（含答案）.pdf
- 2026年重庆市永川区中考化学质检试卷（含答案）.pdf
- 2026年重庆市第一中学校中考化学全真模拟试卷（二）（含答案）.pdf
- 安徽池州市第二中学等校2025-2026学年高一下学期期中物理试卷A（含答案）.pdf
文档评论（0）