FDA药物分类(国外英文资料).doc

FDA药物分类(国外英文资料) Class A: in the womens control study, no drugs were found to be dangerous in the early, middle and late stages of gestation, and the chances of injury to the fetus were minimal. But there is still a possibility that the forward fetus will suffer. Class B: in the control of women, the drug was insufficient or unsubstantiated in the early, middle and late stages of pregnancy. C: animal studies show that the drug causes deformity or death of the fetus, but there is no control over the control of the woman, and the potential harm to the fetus should be weighed against the use of the drug. Class D: drug was evidence of human fetal risk, pregnant women should weigh the pros and cons, only in womens lives or with severe disease. If you can use. X: studies in animals or humans have shown that drugs can be used to cause fetal abnormalities, which may be disabled by pregnant or possibly pregnant women. 1, 2, 3 represents early, medium, and late pregnancy. classification drug level Risk of pregnancy Adverse effects on the fetus Resistance to raw plain class Penicillin class ampicillin amoxicillin piperacillin New penicillin class Cephalosporin class Beta-acylase inhibitors Large ring lactone class erythromycin spiramycin azithromycin josamycin clarithromycin Relying on erythromycin chloramphenicol tetracycline terramycin doxycycline Happy drug novobiocin clindamycin Chlorine clindamycin Amino sugar glycosides tobramycin Butyl amine drug gentamicin kanamycin streptomycin B B B C D C D C B B C/D C C D D D 3 1, 2, 3, 3 1, 2, 3, 1, 2, 3, one 2 3 3 1, 2, 3, 1, 2, 3, 1, 2, 3, A large number of hemolytic anemia, the first choice of antibiotics for pregnant women, and the availability of breastfeeding Nuclear jaundice, liver disorder, lactation Safety is the first choice for pregnancy Safety of animal testing, but no prenatal control study and pregnancy care Liver dysfunction Cholicteric jaundice The granulocytes are reduced, gray infant syndrome, liver damage Microcep