Potassium Phosphates说明书.pdf

POTASSIUM PHOSPHATES INJECTION, USP (3 mM PHOSPHORUS/ mL 4.4 mEq POTASSIUM/ mL) Osmolarity 7.4 mOsmol/ mL Rx Only CAUTION: FOR INTRAVENOUS USE ONLY MUST BE DILUTED AND FILTERED PRIOR TO ADMINISTRATION DESCRIPT ION: Potassium Phosphates Inj ect ion, USP is a sterile, nonpy rogenic , concent rated solut ion containing a mixt ure of monobasic and dibasic potassium phosphate in Water for Injection. It must be diluted prior to administration. Each mL of the solution consists of two phosphate salts provided as follows: Ingredient(s) Phosphorus Potassium Monobasic Potassium 93 mg 170 mg Phosphate - 224 mg Anhydrous or or Dibasic Potassium Phosphate - 236 mg 3 mM 4.4 mEq Anhydrous The solution contains no bacteriostatic agent or other preservative. T he solut ion is intended to prov ide phosphate ion, (PO4-3 ) fo r addit ion to la rge volume infusion fluids for intravenous use. Unused portions should be discarded. CLINICA L PHA RMACOLOGY : Phospho rus in t he fo rm of o rganic and ino rganic phosphate has a va riety of impo rtant bioc hemica l f unct io ns in t he body and is involved in many significant metabolic and enzyme reactions in almost all organs and t issues . It exerts a modify ing inf luence on t he steady state of calcium levels , a buffering effect on acid-base equilibrium and a primary role in the renal excretion of hydrogen ion. Phosphorus is present in plasma and other extracellular fluid, in cell membranes and int racellular fluid,