稀土农用的核酸生物学效应 - 中国生态农业学报.PDFVIP

2009 3 17 2 Chinese Journal of Eco-Agriculture, March 2009, 17(2): 387−392 DOI: 10. 3724/SP.J.1011.2009.00387 * 2 1,2** 王丽红 周 青 (1. 214122; 2. 214122) 稀土农用给中国农业带来巨大的经济效益, 同时稀土环境安全问题也引发中外科学家的关注。核酸 是储存和传递遗传信息的聚合物, 本文从遗传学角度论述了稀土对核酸的影响及其机制。稀土可与核酸分子 结合, 或断裂核酸; 阐述了稀土离子的核酸结合部位及作用方式, 总结了断裂机理, 并提出今后研究的方向。 稀土离子 遗传 核酸 水解 环境安全 : X17 : A : 1671-3990(2009)02-0387-06 Biological effect of agricultural application of rare earth elements on nucleic acid 2 1,2 WANG Li-Hong , ZHOU Qing (1. Key Laboratory for Industrial Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China; 2. School of Environmental and Civil Engineering, Jiangnan University, Wuxi 214122, China) Abstract The extensive application of rare earth elements in agricultural practices in China has brought remarkable economic benefits. However, environmental safety concerns from rare earth element use in agriculture are growing in the Chinese and foreign scientific community. Nucleic acid is a polymer that stores and transfers genetic information. This paper reviews the effect of rare earth on nucleic acid and its mechanisms from the point of view of genetics. It is indicated that rare earth binds with nucleic acid or hydrolyzes nucleic acid. Binding sites of Ln3+ with nucleic acid, mode of action and hydrolytic mechanisms are elucidated. Finally, the future direction of research in this field is proposed. Key words Rare-earth ion, Genetics, Nucleic acid, Hydrolysis, Environmental safety (Received Jan. 16, 2008; accepted May 28, 2008) (Rare Earths, RE) RNA RE , RE ,