淋巴系统及淋巴结成像技术PPT.ppt

The lymphatic system 董龙春 2013.719 the lymphatic system Definition:The lymphatic system is a network of channels, lymph nodes, and organs Function: to collect and return interstitial fluid, and thus help maintain fluid balance to defend the body against disease by producing lymphocytes to absorb lipids from the intestine Organization of The lymphatic system ?lymph transparent, usually slightly yellow, often opalescent[??p?les(?)nt] liquid about 95 percent water the remainder : plasma proteins ,other chemical substances cellular component : lymphocytes two lymphtic ducts lymphoid organs Elephantiasis leg lymph node 400-450 Round/oval/bean shaped Different size,usually 1cm Superficial and deep lymph node respond to antigens and generate antibodies——Clear harmful substances，“Filter” lymph node pathology pathology pathology question need to be considered seriously Whats the different changes between the manlignant LN and the benign reactive hypertrophy LN? Once out-antigen stimulated the germinal center development,the extracelluar become more crowd. Consequently,will it cause limitation of the water diffusion? hyperintensity on DWI?How to distinguish from metastatic LN? Lymph Node Imaging important role： provide accurate pretreatment staging of the tumor for planning medical, surgical, and radiation interventions monitor response to therapy and provide surveillance after curative treatment Morphology measurements are still the most frequently used method for discriminating malignant from non-malignant lymph nodes, but are insufficiently accurate. Lymph Node Imaging Lymph Node Imaging(CT/MRI) Lymph Node Imaging(CT/MRI) Lymph Node Imaging(ultrasound) Lymph Node Imaging(ultrasound) Lymph Node Imaging(ultrasound) Lymph Node Imaging Lymph Node Imaging(DWI) Lymph Node Imaging(MRI) MR lymphography(USPIO） PET/CT for LN imaging Imaging mechanism: the glucose analog 18F-FDG, could be avidly taken up by cells with increased rates of glycolysis. Weak point: