盆腔良性病变血清CA125水平测定的临床意义.pdfVIP

标记免疫分析与临床 2007年 l2月第l4卷第4期 215 盆腔良性病变血清CA1 25水平测定的临床意义 姚 昊，叶一秀，欧阳晓辉，孙利群，杨晓红 (解放军总医院第二附属医院核医学科，北京 100091) 摘要：评价血清CA125水平检测在妇科良性病变患者的临床意义。回顾分析了71例妇科良性病变患者，65例 卵巢癌患者和53名正常对照者的临床资料，发现卵巢癌和妇科良性病变组血清CA125水平均明显高于对照组， 卵巢癌组CA125水平明显高于妇科良性病变组和盆腔结核组血清CA125水平明显高于其他妇科良性病变。结 合临床其他资料，血清CA125水平检测有助于卵巢癌和盆腔结核病的诊断。 关键词：盆腔肿瘤； 结核病； 子宫内膜异位症； CA125抗原 中图分类号：R737．3 文献标识码：A 文章编号：1006-1703(2007)04—0215一O2 Clinical Significance of Serum CA125 Levels in the Patients with Pelvic Benign Pathological Changes YAO Hao，YE Yi—xiu．OUYANG Xiao—hui。et a1． (Department of Nuclear Medicine，The Second AffiliatedHospital of General Hospital of P1 A，Beijing 100091，China) Abstract：To evaluate the clinica1 significance of serum CA125 1evels detection in patients with pelvic benign pathological changes，7 1 patients with pelvic benign pathological changes，65 pa— tients with ovarian epithelial cancer and 53 normal controls were analyzed retrospective1y，The results showed that the serum CA1 25 levels in the patients with ovarian epithelial cancer and pelvic benign pathological changes were higher than that of in normal control，while the serum CA1 25 levels in patients with ovarian epithelial cancer were higher than the patients with pelvic benign pathological changes．The serum CA1 25 levels in patients with pelvic tuberculosis were higher than the patients with other pelvic benign pathological changes．Combining with other clinical information，the serum CA1 25 levels may be helpful in the diagnosis of ovarian epitheli— al cancer and pelvic tuberculosis． Key words：Pelvic tumor； Tuberculosis； Endometriosis； CA1 25 糖类抗原CA125早期作为卵巢上皮癌的血清 材料和方法 肿瘤标记物，其抗原决定簇存在于蛋白质部分，目 前主要用于卵巢癌的诊断和疗效观察u]。研究表