肥厚型心肌病患者左室心肌收缩期应变率的速度向量成像定量分析.pdfVIP

· 39O · 第二军医大学学报 2008年4月第29卷第4期 http：／／w~w．ajsmmu．Cn Academic Journal of Second Military Medical University，Apr．2008，Vo1．29，No．4 DOI：10．3724／SP．J．1008．2008．00390 ·论 著· 肥厚型心肌病患者左室心肌收缩期应变率的速度向量成像定量分析 江 鸿 ，智 光，阎国辉，侯海军，周 肖，徐 勇 解放军军医进修学院，北京 100000 [摘要] 目的：应用速度向量成像(VVI)技术，探讨肥厚型心肌病(HCM)患者左室心肌收缩期应变(￡)、应变率(sR)的改变。 方法：选取2O例室间隔肥厚的HCM患者和 2O例年龄配对的健康志愿者，在 VVI模式下，分别取心尖四腔、三腔和二腔切 面。分析左室18个室壁节段的￡和SR曲线，测量收缩期峰值。结果：对照组左室心肌收缩期SR值为(一1．O6 4-0．09)／s， HCM组为(～0．744-0．16)／s，HCM组左室心肌各节段收缩期SR较对照组明显减低，差异有统计学意义(P0．05)。HCM 组各节段收缩期SR减低不仅仅限于肥厚部位，也存在于非肥厚部位。结论 ：HCM患者左室心肌收缩期￡和SR明显低于对 照组，HCM患者收缩期￡和SR的减低不仅限于肥厚部位。 [关键词] 肥厚型心肌病；速度向量成像；应变；应变率；左心室；心肌收缩期 [中图分类号] R 542．2 [文献标志码] A [文章编号] 0258—879X(2008)04—0390—05 Quantitative analysis of left ventricular systolic strain and strain rate in hypertrophic cardiomyopathy patients by velocity vector imaging JIANG Hong ，ZHI Guang，YAN Guo—hui，HOU Hai-jun，ZHOU Xiao，XU Yong PLA Postgraduate Medical Schoo1．Beijing 10000．China [ABSTRACT] Objective：To observe the changes of left ventricular(LV)systolic strain(￡)and strain rate(SR)in patients with hypertrophic cardiomyopathy(HCM)and normal healthy subjects by velocity vector imaging(VVI)．Methods：Twenty patients with HCM and 20 age-matched healthy adults were enrolled in this study．The peak systolic￡，SR of 18 segments in the 4，3 and 2-chamber views were measured by VVI_Results：It was found that the systolic SR was(一1．06 4-0．09)／s in the healthy control group and(一0．74 4-0．1 6)／s in the HCM group(P0．05)．The reduction of systolic SR in HCM group was found not only at the hypertrophic regions but also at normal regions．Conclusion：The systolic￡and SR in HCM group is lower than that in the normal control group．The reduction of systolic￡and SR in HCM group is not limited to the hypertrophic region． [KEY WORDS] hypertrophic cardiomyopathy；velocity vector imaging；str